Senior Scientist - SBX Molecular Engineering

Roche Diagnostics acquired Stratos Genomics ( https://www.stratosgenomics.com/ ) in 2020 for its unique chemistry that advances DNA sequencing by nanopore, Sequencing by Expansion (SBX™). You will engineer and synthesize the molecular building blocks for our novel technology. The Molecular Engineering group is a passionate team. We are looking for people who are excited and want to make SBX successful. Please include a cover letter outlining why you want to work with us and how you would contribute.

Essential Functions

• Research, design and execute, innovative and well-controlled experiments, with high attention to detail.

• Identify and troubleshoot problems in creative ways.

• Contribute to the definition and timely achievement of project goals.

• Participate in the production of reagents and starting materials.

• Perform data analysis and protocol development.

• Maintain accurate, detailed and reliable laboratory records.

• Present findings at group or departmental meetings.

• Maintain the lab’s cleanliness and organization.

• Develop and propose improved processes to fulfill the above functions.

• Other duties as assigned.

Education & Experience:

• Bachelor’s degree in Biological/Life Sciences, Chemistry, Organic Chemistry, Chemical Engineering, Biochemistry or related field, or equivalent combination of education and work experience, MS or PHD Preferred. 8+ years of industry experience, less with advanced degrees.

• Minimum of 2 years laboratory experience with complex DNA/RNA oligo-synthesis or advanced nucleotide/heterocyclic chemistry.

• Ideal candidates will have:

  • Demonstrated ability to understand and develop chemistry for:

    • Nucleotides

    • Phosphoramidites

    • Heterocycles

    • Amino Acids

    • Bio-conjugations

  • Mature understanding of how to work with chemical and biochemical samples, including sample handling, reactivity, purification and storage.

  • Technical background in next-generation DNA sequencing

  • Experience with HPLC, MS, NMR, automated DNA synthesizers, inert atmosphere chambers, and manual pipetting.

  • A flexible schedule during COVID lab census restrictions. Weekly or longer rotations either in the morning or afternoon and occasional weekends.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us at US.Accommodation@roche.com .