Associate Director Project Management

The Company:

Eloxx Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates (designed to be eukaryotic ribosomal selective glycosides) that are formulated to treat rare and ultra-rare premature stop codon diseases. Premature stop codons are point mutations that disrupt protein synthesis from messenger RNA. As a consequence, patients with premature stop codon diseases have reduced or eliminated protein production from the mutation bearing allele accounting for some of the most severe phenotypes in these genetic diseases. These premature stop codons have been identified in over 1,800 rare and ultra-rare diseases. Read-through therapeutic development is focused on extending mRNA half-life and increasing protein synthesis by enabling the cytoplasmic ribosome to read through premature stop codons to produce full-length proteins. Eloxx’s lead investigational product candidate, ELX-02, is a small molecule drug candidate designed to restore production of full-length functional proteins. ELX-02 is in the early stages of clinical development focusing on cystic fibrosis and cystinosis. ELX-02 is an investigational drug that has not been approved by any global regulatory body. Eloxx’s preclinical candidate pool consists of a library of novel drug candidates designed to be eukaryotic ribosomal selective glycosides identified based on read-through potential. Eloxx recently announced a new program focused on rare ocular genetic disorders.

Eloxx is headquartered in Watertown, MA, with a regional office in Rehovot, Israel.

The Role:

Eloxx Pharmaceuticals is looking for Associate Director of Program Management to facilitate cross-functional projects in a fast- paced environment. This role will be responsible for maintaining, integrating, and executing plans, schedules and budgets. This is a highly visible role, working closely with technical leads to develop program strategies and operational plans that will guide efficient program execution to achieve program objectives and stakeholder goals. This position is based in our Watertown, MA Headquarters.

Responsibilities:

• Coordinate with functional heads to develop program plans and track progress
• Maintain project plans, study tracking tools, decision logs and team calendars to ensure deadlines and deliverables are met on or ahead of schedule
• Coordinate team and sub-team meetings, including setting agendas, capturing meeting minutes, and ensuring appropriate follow-up for action items
• Work with functional leads to manage with team review of key documents
• Prepare program presentations for executive management presentations
• Manage vendor contracts and review of vendor invoices
• Identify and anticipate program risks and develop mitigation and contingency plans, direct cross-functional communication, and team cohesiveness, appropriately elevate issues in a timely manner
• Managing a multi-functional team in the strategic development and operational execution of an early-stage drug candidate

Competencies Include:

• Experience in preclinical drug development, preIND CMC development, and IND enabling studies
• Experience in preclinical regulatory activities, such as informal FDA communications, preIND meetings, and IND preparation and submission
• Vendor management
• Excellent communication and interpersonal skills
• Aptitude for organizational detail and ability to manage highly complex projects
• Ability to interact across all levels of the organization
• Capacity to complete tasks independently in a highly regulated environment
• Flexibility to function well within a team environment and within condensed timelines
• Ability to verbalize complex study issues and demonstrated problem-solving ability

Education:

• BS in Chemistry, Biology, or other scientific field
• MBA preferred

Experience:

• 10+ years in the pharmaceutical/biopharmaceutical industry, 7+ in a project management role, 3+ years working with senior leadership
• PMP certification required
• Proficient in MS Project and OnePager or Office Timeline
• Advanced knowledge of MS Excel, including charts and pivot tables

What Eloxx Can Offer You:
In addition to offering competitive salaries, Eloxx Pharmaceuticals offers a full benefit package including healthcare, dental, vision, short and long-term disability, life insurance, 401(k) retirement saving plan, and paid holiday and vacation days.

Eloxx Pharmaceuticals is an Equal Opportunity Employer and does not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.